INDICATORS OF THE QUALITY OF LIFE OF PATIENTS WITH COLORECTAL CANCER: A LITERARY REVIEW.

Abstract

Relevance: GLOBOCAN estimates that 1.9 million new cases of colorectal cancer (CRC) and 935,000 deaths from CRC were detected in 2020, accounting for one in 10 cancer cases and deaths. According to the Oncological Service of the Republic of Kazakhstan (RK), in 2019, CRC ranked 5th in terms of morbidity and mortality among all localizations. With a survival time of more than 5 years, one of the main criteria that determine the condition of patients and the effectiveness of treatment is the quality of life. Understanding quality of life is essential to assessing the full impact of a disease on an individual, family and community.

             The purpose of this study: To study the indicators of the quality of life of patients with colorectal cancer and thereby introduce into the RK the Kazakh validation of the EORTC QLQ-CR-2 questionnaire.

          Results of the study: The quality of life of patients with CRC in the world is relatively low in terms of physical, mental, social, and clinical aspects. The most important factors affecting quality of life were sexual dysfunction, body dissatisfaction in ostomy patients, chronic recurrent diarrhea, symptoms of distress, and high fatigue. The patient's lifestyle, age, gender, stage of the disease, psychoemotional status of a person - all this affects the quality of life of patients with CRC. It should also be noted that people with CRC who were physically active reported a better quality of life than those who were not physically active.

           Conclusion: To date, in the RK, no study has been conducted to study the quality of life of patients with CRC. In this regard, it is necessary to conduct a study to understand the quality of life of patients with CRC using the Kazakh version of the EORTC QLQ-CR-2 questionnaire. Within the framework of grant funding for young scientists IRN AP09058432 KN MES RK, in the near future we plan to conduct such a study and will share the results.

         Key words: colorectal cancer, patient quality of life, EORTC QLQ-CR-2, linguistic validation, malignant neoplasm.