Endoscopic treatment of Barrett's esophagus in Kazakhstan.
Keywords:
Barrett’s esophagus (BE), metaplasia, endoscopy, esophageal neoplasms, gastroesophageal refluxAbstract
Relevance: Barrett’s esophagus (BE) is a special disease characterized by metaplasia of the flat epithelium of the esophagus. The main danger of esophageal epithelial metaplasia is the high probability of developing a malignant neoplasm at the site of the lesion – esophageal adenocarcinoma or cancer of the cardio esophageal zone.
The study aimed to evaluate the clinical effectiveness of new BE endoscopic treatment methods for their subsequent implementation
in wide practice throughout the Republic of Kazakhstan.
Methods: This article presents cases of clinical use of argon plasma coagulation of dysplasia lesions less than 2.0 cm in two patients with Barrett’s esophagus and the use of loop resection of dysplasia lesions more than 2.0 cm in three patients with Barrett’s esophagus.
Results: All the presented cases have shown the effectiveness of applied treatment. Control morphological examination showed no signs of BE in the epithelium.
Conclusion: The presented article describes the results of the introduction of endoscopic BE treatment methods in our clinic and is available for wide implementation throughout Kazakhstan. A widespread introduction of endoscopic treatment of precancerous pathology will reduce the incidence of esophageal cancer in the Kazakhstani population.