NEW ASPECTS IN THE USE OF MULTIMODAL ANALGESIA DURING SURGICAL INTERVENTIONS IN CANCER PATIENTS: A LITERATURE REVIEW

Abstract

Relevance: Multimodal analgesia is an important tool in postoperative pain management in cancer patients. It provides a comprehensive approach that minimizes side effects, improves recovery, and improves the patient’s quality of life in the postoperative period.
The study aimed to generalize current data from systematic reviews, meta-analyses, and randomized controlled trials that consist of strategies and new aspects of multimodal analgesia for oncological surgery. An important aspect is the identification of effective methods for pain management in patients who have undergone surgery due to cancer.
Methods: The Cochrane Library, PubMed, and Embase were searched to identify randomized controlled trials, systematic reviews,
and meta-analyses published in English from 2019 to 2024 that focused on the results of the use and comparison of different methods of
multimodal analgesia during surgical interventions in patients with cancer.
Results: As a result of the analysis of data from large scientific studies and meta-analyses, the advantage of opioid-sparing methods in multimodal analgesia was established, as well as the widespread use of ultrasound-guided peripheral blocks.
Conclusion: A multimodal standardized method of pain relief with ropivacaine (regional blocks) in combination with acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) has the best analgesic effect in patients undergoing surgery for cancer and can effectively inhibit early postoperative inflammatory reactions and promote postoperative recovery without increasing the incidence of adverse reactions and complications.